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β-Propiolactone 269040050 ACROS


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beta-Propiolactone, 98%, pure
 
 
 
General 
^ 
Product Name 
beta-Propiolactone
2-Oxetanone
CAS RN 
57-57-8
ACD Code 
MFCD00005169
Structure 
Molecular Formula 
Molecular weight 
72.06
Pack size 
Catalog
Qty / UM
 269040050
 5 ML
 269040250
 25 ML
 269041000
 100 ML
Physical 
^ 
Density 
1.146
Refractive index 
1.412
 - 1.414
Boiling Point (°C) 
162
Melting Point (°C) 
-
33
Flash Point (°C) 
70
Safety 
^ 
GHS Pictogram 
   
GHS Signal Word 
Danger
GHS H statment 
H319:
Causes serious eye irritation
H315:
Causes skin irritation
H330:
Fatal if inhaled
H350:
May cause cancer
GHS P statment 
P308 + P313:
IF exposed or concerned: Get medical advice/attention
P304 + P340:
IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P302+ P352:
IF ON SKIN: Wash with plenty of soap and water
P305 + P351 + P338:
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P280:
Wear protective gloves/protective clothing/eye protection/face protection
Hazard 
T+:
Very toxic
Risk 
45:
May cause cancer.
26:
Very toxic by inhalation.
36/38:
Irritating to eyes and skin.
Safety 
53:
Avoid exposure - obtain special instructions before use.
45:
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
^ 
 
Building Blocks  >  Organic Building Blocks  >  Carbonyl Compounds  >  Lactones
Other 
^ 
Infrared 
Parameter 
EINECS 
200-340-1
Solubility 
Solubility in water: 37% in water Solubility in other solvents: miscible with alcohol, acetone, ether and chloroform
Origin 
synthetic
References: Literature 
A facile method for synthesis of three carbon-homologated carboxylic acid by regioselective ring-opening ofbeta-propiolactones with organocopper reagents: M. Kawashima et al.; Tetrahedron 45, 403-412 (1989).Inactivation of the Hutchinson strain of hepatitis non-A, non-B virus in intravenous immunoglobulin by beta-propiolactone: Stephan W. et al.; J. Med. Virol, 26(3), 227-32 (1988).
Reference: Beilstein 
17,130
Reference: Fieser 
01,957; 15,224
Reference: Merck 
14,7820
3D model 
 
Building Blocks Organic Building Blocks Carbonyl Compounds Lactones
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